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KMID : 0603520010060040201
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Journal of Korean Association of Cancer Prevention
2001 Volume.6 No. 4 p.201 ~ p.213
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Development of Dietary Assessment Tools for an Epidemiological Study with a Small Number of Participants
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Yoon Ha-Chung
Benamouzig Robert
Yoo Keun-Young
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Abstract
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Environmental factors, including diet and chemo-preventive agents such as aspirin, vitamins and antioxidants, seem to be implicated in colorectal carcinogenesis. A randomized intervention trial is underway to test the efficacy of aspirin on colorectal adenoma recurrence. To understand dietary patterns of participants in this trial and to identify dietary factors associated with colorectal adenoma development, a case-control study was designed. The present study aimed at developing and validating dietary assessment instruments for use in a small study population. A food composition database as well as programs for data-entry and for converting to daily dietary intake were developed. Estimated dietary intakes were compared to dietary patterns available on the French population. We observed highly positive correlations with the nutritional intakes estimated by the E3N study`s instruments for the same population(r=0.94 for total calorie intake; p<10-3). Our dietary assessment instruments are capable of measuring dietary intakes within the framework of the French population`s real dietary pattern and rank them correctly in the study population. The easy use of these dietary assessment instruments shows their potential to be used in other studies with a small number of subjects, aiming at evaluating associations between diet and disease.
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KEYWORD
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Colorectal adenomas, Dietary assessment tools, Food frequency questionnaire
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